FACULTY of ARTS AND SCIENCESDEPARTMENT OF STATISTICS


VİLDA PURUTÇUOĞLU

Picture of the person
Prof. VİLDA PURUTÇUOĞLU
Room No: 
131
Telephone: 
+90 (312) 210-5319
Fax No: 
+90 (312) 210-2959
E-mail: 
vpurutcu@metu.edu.tr
Chair of Biomedical Engineering (BME) Graduate Programme, Erasmus Coordinator of BME
Education: 
  • M.Sc., Department of Economics, Middle East Technical University, Turkey, 2018-current.
  • B.Sc., Department of Philosophy, Anadolu University, Turkey, 2017-2020.
  • Ph.D., Department of Mathematics and Statistics, Lancaster University, U.K. 2004-2007.
  • M.Sc.,  Department of Statistics, Middle East Technical University, Turkey, 2002-2004.
  • Minor,: Department of Economics, Middle East Technical University, Turkey, 2000-2002.
  • B.Sc., Department of Statistics, Middle East Technical University, Turkey, 1998-2002.
 
 Recent Academic Posts
  • October 2018-current, Professor, Dept. of Statistics, METU 
  • December 2012-October 2018, Associate Professor, Dept. of Statistics, METU.
  • February 2011-current, Affiliated Faculty Member, Dept. of Biomedical Engineering, METU.
  • January 2011-current, Affiliated Faculty Member, Informatics Institute, METU.
  • November 2010-current, Affiliated Faculty Member, Institute of Applied Mathematics, METU.
  • August 2010-December 2012, Assistant Professor, Dept. of Statistics, METU.
 
 Recent Professional Activities
  • June 2020 - June 2022, Associate Editor of Biometrics 
  • 2020 - 2023, Awards Fund Committee Member, International Biometric Society (IBS). 
  • June 2019 - current, Country Representative, Eastern Mediterranean Region of the International Biometric Society (EMR-IBS).  
  • June 2019 - current, Chair, Graduate Programme of Biomedical Engineering, METU.
  • June 2019 - current, Erasmus Coordinator, Graduate Programme of Biomedical Engineering, METU.
  • April 2019 - current, Education Commission Member, Faculty of Arts and Sciences, METU.
  • Dec. 2018- current, Editorial Board of International Journal of Industrial Engineering and Operational Research.
  • Dec. 2018-current, Advisory Board of the Journal of Data Science and Applications.
  • March 2016 - current, Management Committee Member for Turkey in the COST grant CA15109. 
  • 2010-current, Advisory Board and Regular Referee for Journal of Biostatistics - Turkish Clinics. 
  • 2013-current, Internship Coordinator, Department of Statistics, METU. 
  • Nov. 2016 - March 2020, Biomolecular Engineering Track Representative, Department of Biomedical Engineering, METU. 
  • 2016 - 2019, Awards Fund Committee Member, International Biometric Society (IBS). 
  • Sept. 2017- Oct. 2018, Faculty Executive Board Member,Faculty of Arts and Sciences, METU.

Recent Scholarships and Awards
  • 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018:  Academic Performance Award, Faculty of Art and Science, METU
  • 2015: Finalist of Sabri Ülker Science Award, Sabri Ülker Food Research Foundation.

       (Note: The complete list of sholarships and awards can be found in the attached CV).



 
Research Interests: 
  • Bioinformatics, Systems Biology, High Dimensional Data, Neuroscience, Social Statistics.
 
Recent Projects
  1. Co-investigator, January 2020-July 2021, Scientific and Technological Research Council (TÜBİTAK - 1003 Programme). Project title: Development of hardware and software infrastructure for physiological human data for use in human-machine applications. Project no: 117E650. 

  2. Principal investigator, January 2020-January 2022, Scientific Research Project (BAP1), METU. Project title: Approximate stochastic simulation algorithms in protein-protein interaction networks. Project no: BAP-10282.

  3. Secondary-investigator, March 2016-March 2021, European Community 7th Framework Programme (COST Programme). Project title: European network for statistical network science. Project no: CA15109.  investigator

  4. Tutorial speaker,  26-28 September 2019, Scientific and Technological Research Council (TUBITAK - 2237-B Programme). Project title: Project training in engineering (MAPRE).

  5. Principal investigator, January 2017-December 2018, Scientific Research Project (BAP1), METU. Project title: Inference of the Gaussian graphical model and lasso regression via the modi ed maximum likelihood method. Project no: BAP-01-09-2017-002.

  6. Principal investigator, January 2017-December 2018, Scientific Research Project (DAP1), METU. Project title: Collection of genetic information, analysis and modeling of the cervical cancer with risk factors. Project no: BAP-08-11-2017-035.

  7. Principal investigator, January 2016-June 2017, Scientific Research Project (BAP1), METU. Project title: Alternative approaches, inference and copulas in deterministic modellings of complex biological systems. Project no: BAP-01-09-2016-002. 

  8. Principal investigator, April 2015-April 2017, Scientific and Technological Research Council (TUBITAK - 1001 Programme). Project title: Application of copulas in inference of biological networks via Gaussian graphical models and parameter estimation. Project no: 114E636. 

  9. Principal investigator, January 2014-January 2017, METU Research and Development Project (AGEP Programme). Project title: Simulation of biochemical systems via stochastic simulation algorithms and extensions of these methods by including impulses, Project no: BAP-08-11-2014-007.

          (Note: The complete list of projects and grants can be found in the attached CV).

 

Selected Publications: 

Books

  1. Purutçuoğlu, V. and Ayyıldız, E. (December 2014) " Statistics in the Field of Bioinformatics (Biyoinformatik Alanında Istatistik-in Turkish) ”, Nobel Publisher. ISBN: 978-605-320-008-6 (http://www.nobelyayin.com/detay.asp?u=4309)
  2. Wit, E., Vinciotti, V., and Purutçuoğlu, V.  (December, 2016) “ Statistics for Biological Networks: How to Infer Networks from Data ”, Chapman and Hall/CRC. ISBN: 978-439841470 (http://www.amazon.com/Statistics-Biological-Networks-Chapman-Interdisciplinary/dp/1439841470)

 
Recent Chapters in Books  
  • Purutçuoğlu, V. and Farnoudkia, H. (2020) "Vine copula and artificial neural network models to analysis breast cancer data". Chapter in: Artificial Intelligence for Data-Driven Medical Diagnosis. Editors: D. Gupta, U. Kose, B. L. Nguyen, S. Bhattacharyya. De Gruyter (In print).

  • Ağyüz, U., Purutçuoğlu, V., Purutçuoğlu, E. and Ürün, Y. (2020) "Construction of a new model to investigate breast cancer data". Chapter in: Modeling, Dynamics, Optimization and Bioeconomics IV. Editors: A. Pinto and D. Zilberman. Springer (In print).

  • Erkuş, E. C. and Purutçuoğlu, V. (2020) "Hidden oscillation feature extraction in ECG data via multiple-FOD method". 47-56. Chapter in: Lecture Notes on Data Engineering and Communications Technologies. Editors: T. Yiğit, U. Köse. Springer..

  • Kaygusuz, M. A. and Purutçuoğlu, V. (2020). "Comparative study for model selection in sparse biological networks and a new alternative approach".  107-126. Chapter in: Lecture Notes on Data Engineering and Communications Technologies. Editors: T. Yiğit, U. Köse. Springer.

  • Doğan Dar, E., Purutçuoğlu, V.  and Purutçuoğlu, E. (2020) "Detection of HIV-1 protease cleavages sites via hidden Markov model and physicochemical properties of aminoacids". 171-193. Chapter in: Numerical Solutions of Real-Life Nonlinear Phenomena. Editors: J. A. T. Machado, N. Özdemir, D. Baleanu. Springer.

  • Seçilmiş, D., Ağraz, M. and Purutçuoğlu, V.  (2019) “Two novel non-parametric models in the construction of biological networks ”. Chapter in: Information Complexity and Statistical Modeling in High Dimensions with Applications. Editors: O. Arslan. Springer (In print).

  • Ayyıldız, E. and Purutçuoğlu, V. (2019) “Generating various types of graphical models via MARS ”. Chapter in: Information Complexity and Statistical Modeling in High Dimensions with Applications. Editors: O. Arslan. Springer (In print). 

  • Seçilmiş, D. and Purutçuoğlu, V. (2019) “Modeling of biochemical networks via classification and regression tree methods ”. 87-102. Chapter in: Mathematical Methods in Engineering. Editors: K. Taş, D. Baleanu and J.A. Mashado. Springer. 

  • Ağraz, M. and Purutçuoğlu, V. (2019) “Empirical copula in the detection of batch effects ”. 25-39. Chapter in: Mathematical Methods in Engineering. Editors: K. Taş, D. Baleanu and J.A. Mashado. Springer.

  • Tuncer, G. and Purutçuoğlu, V. (2018) “ Major simulation tools for biochemical networks ”. 443-46. Chapter in: Modelling, Dynamics, Optimization and Bioeconomics III. Editors: A. Pinto, Z. Zilberman. Springer.

  • Purutçuoğlu, V. (2018) “ Stochastic modelling of biochemical networks and inference of model parameters ”. 369-385. Chapter in: Modelling, Dynamics, Optimization and Bioeconomics III. Editors: A. Pinto, Z. Zilberman. Springer.


Recent Articles   

  • Erkuş, E.C. and Purutçuoğlu, V. (2020) "Outlier Detection and Quasi-periodicity Optimization Algorithm: Frequency Domain Based Outlier Detection (FOD)".  European Journal of Operational Research, https://doi.org/10.1016/j.ejor.2020.01.014, 1-15.

  • Ağraz, M. and Purutçuoğlu, V. (2020) "Long-tailed graphical model and frequentist inference of the model parameters for biological networks". Journal of Statistical Computation and Simulation, 90 (9), 1591-1605.

  • Farnoudkia, H. and Purutçuoğlu, V. (2019) “ Copula Gaussian graphical modelling of biological networks and Bayesian inference of model parameters ”, Scientia Iranica, 26 (4), 2495-2505.

  • Erkuş, E C., Purutçuoğlu, V., Purutçuoğlu, E. (2019) "Detection of abnormalities in heart rate using multiple Fourier transforms", International Journal of Environmental Science and Technology, 16, 5237–5242.

  • Bülbül, G. B., Purutçuoğlu, V., Purutçuoğlu, E. (2019) "Novel model selection criteria on sparse biological networks", International Journal of Environmental Science and Technology, 16, 5359–5364.

  • Ağraz, M. and Purutçuoğlu, V. (2019) “ Extended lasso-type MARS (LMARS) model in the description of biological network ”, Journal of Statistical Computation and Simulation, 89 (1), 1-14.

  • Bahçivancı, B., Purutçuoğlu, V., Purutçuoğlu, E., Ürün, Y. (2018) "Estimation of gynecological cancer networks via target proteins", Journal of Multidisciplinary Engineering Science and Technology, 5 (12), 9296-9302.

  • Ayyıldız, E. and Purutçuoğlu, V. (2018) “Modeling of various biological networks via LCMARS”, Journal of Computational Science, 28, 148-154.

  • Ayyıldız, E. and Purutçuoğlu, V. (2018) “ Is it necessary to apply the outlier detection for protein-protein interaction data? ”, Journal of Biostatistics-Turkish Clinics, 10 (3), 173-186.

  • Altıntan, D., Purutçuoğlu, V.  and Uğur, Ö. (2018) “ Impulsive expressions in stochastic simulation algorithms ”, International Journal of Computational Methods, doi: 10.1142/S021987621750075X, 15 (1), 1750075.1-16.

  • Altıntan, D. and Purutçuoğlu, V. (2018) "Exact stochastic simulation algorithms and impulses in biological systems", International Journal of Computational and Experimental Science and Engineering, 4 (2), 41-47.

  • Ayyıldız, E., Purutçuoğlu, V.  and Weber, G.W. (2018) “ Loop-based conic multivariate adaptive regression splines is a novel method for advanced construction of complex biological networks ”, European Journal of Operational Research,doi: 10.1016/j.ejor.2017.12.011, 270, 852-861. 

          (Note: The complete list of publications can be found in the attached CV.)